Scientists have developed a simple DNA test that can identify 18 early-stage cancers that experts say could represent a medical “gamechanger”.

Cancer accounts for one in every six deaths worldwide, but early detection can significantly improve outcomes. Existing screening tests have drawbacks, including invasiveness, cost and low levels of accuracy for early stage disease.

Now US researchers have designed a test that analyses proteins in the blood and can pick up 18 early stage cancers, representing all main organs in the human body.

Specific blood proteins could already be used for early detection and monitoring, but until now tests have lacked sensitivity – accuracy of picking up those with cancer – and specificity – accuracy of excluding those without cancer, the researchers said.