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    38 months ago

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    In an orchestra, one instrument played out of synchrony with the rest can disrupt the coherence of the entire piece of music," says Robert Desimone, director of MIT’s McGovern Institute for Brain Research and one of the senior authors of the study.

    André Bastos, an assistant professor of psychology at Vanderbilt University, is also a senior author of the open-access paper, which appears today in Nature Neuroscience.

    Together, groups of neurons with similar patterns generate oscillations of electrical activity, or brain waves, which can have different frequencies.

    In addition to working memory, the brain’s cortex also is the seat of thought, planning, and high-level processing of emotion and sensory information.

    This data included recordings of electrical activity from three human patients who had electrodes inserted in the brain as part of a surgical procedure they were undergoing.

    They are also investigating whether rebalancing the oscillations could alter behavior – an approach that could one day be used to treat attention deficits or other neurological disorders, the researchers say.


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