I had a similar problem with an NUC where the install would work but was unbootable after. In my case the USB showed up as both a BIOS and UEFI boot device and the mobo was picking the legacy mode. This made the install a legacy boot install which was not bootable.
To fix it I had to manually choose to boot the install USB’s UEFI mode.
What make and model, what problem is it giving you?
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I had a similar problem with an NUC where the install would work but was unbootable after. In my case the USB showed up as both a BIOS and UEFI boot device and the mobo was picking the legacy mode. This made the install a legacy boot install which was not bootable.
To fix it I had to manually choose to boot the install USB’s UEFI mode.